Alterations in Hematological Parameters: Could it be a Marker in Diabetes Mellitus?

This review discussed the mechanism by which hyperglycemia produces changes in blood constituents, the effect of hyperglycemia on different blood constituent with special stress on anemia, as well as its influence on immunological changes and cancer susceptibility. The predictive value of changes in these blood constituent and the development of diabetic complications as well as blood constituent changes produced by drugs used in diabetics (hypoglycemic agents, lipid lowering agents, angiotensin converting enzyme inhibitors, angiotensin receptor antagonists and anti platelet agents) were also dealt with. Lastly, the reversible changes in blood constituent on improving glycemic control were mentioned.